Daily Program

*The program is tentative and subject to change.

07:55-08:00
Education Day Opening
GBR, 1F
08:00-09:00
Molecular Pathology 2022
Molecular Pathology 2022
GBR, 1F
Chair(s)
Se Hoon Kim (Severance Hospital, Yonsei University, Korea)
08:00-08:20
The trend of New WHO classification Pre-recording Only
David Capper (Charité University, Germany)
08:20-08:40
Update in New WHO Classification- Adult glioma-IDH-wildtype Pre-recording + Live Q&A
Arie Perry (University of California, San Francisco (UCSF), USA)
08:40-09:00
Update in New WHO Classification - Adult glioma-IDH-mutant Pre-recording + Live Q&A
Ho-Keung Ng (Chinese University of Hong Kong, Hong Kong)
09:00-10:20
Plenary Session 1
Cell of Origin
GBR, 1F
Chair(s)
Hyunggee Kim (Korea University, Korea)
09:00-09:40
Glioblastoma origin and functional heterogeneity Pre-recording Only
Luis F. Parada (Memorial Sloan Kettering Cancer Center, USA)
09:40-10:20
New targets for cancer stem cells: redox regulation and differentiation Pre-recording + Live Q&A
Hideyuki Saya (Keio University, Japan)
10:40-11:40
Education Session 1
Recent Progress of Artificial Intelligence in Neuro-oncology Imaging
GBR 101+102, 1F
Chair(s)
Seung Hong Choi (Seoul National University, Korea)
10:40-11:00
AI and radiomics in glioma Pre-recording Only
Philipp Vollmuth (Heidelberg University Hospital, Germany)
11:00-11:20
Artificial Intelligence in Neuro-Oncology Imaging: Promising Applications and Challenges Onsite
Sung Soo Ahn (Severance Hospital, Yonsei University, Korea)
11:20-11:40
Perfusion MRI analysis for radiogenomics of gliomas: Deep-learning approach Onsite
Kyu Sung Choi (Seoul National University, Korea)
10:40-11:40
Education Session 2
Immune Microenvironment in Gliomas
GBR 103, 1F
Chair(s)
Chul-Kee Park (Seoul National University, Korea)
10:40-11:00
New players in immune microenvironment for glioma management Zoom Live Lecture
Michael Lim (Stanford University, USA)
11:00-11:20
T cell Heterogeneity in glioma microenvironment Onsite
Eui-Cheol Shin (Korea Advanced Institute of Science and Technology (KAIST), Korea)
11:20-11:40
Crosstalk between immune and molecuar microenvironment in gliomas Pre-recording Only
Michael Platten (University Hospital Mannheim, Heidelberg University, Germany)
10:40-11:40
Education Session 3
Conducting Neuro-oncology Clinical Trials
GBR 104+105, 1F
Chair(s)
Susan Chang (University of California, San Francisco (UCSF), USA)
Seung Ho Yang (The Catholic University of Korea, Korea)
10:40-11:10
Ongoing Clinical Trials for Recurrent High Grade Gliomas: How Can We Make a Breakthrough? Pre-recording + Live Q&A
David A. Reardon (Harvard Medical School, USA)
11:10-11:40
Challenges of Neuro-Oncology Clinical Trials and Future Perspectives Pre-recording Only
Michael Weller (University Hospital Zurich, Switzerland)
11:40-12:40
Education Session 4
Pediatric Type Diffuse Glioma
GBR 101+102, 1F
Chair(s)
Susan Chi (Harvard Medical School, USA)
Jeong Ok Hah (Yeungnam University, Korea)
11:40-12:10
Pediatric type diffuse glioma-Low grade glioma Pre-recording Only
Cynthia Hawkins (The Hospital for Sick Children, The University of Toronto, Canada)
12:10-12:40
Pediatric type diffuse glioma-High grade glioma Pre-recording Only
Guido Reifenberger (Heinrich-Heine-University, Germany)
11:40-12:40
Education Session 5
Spatio-Temporal Evolution of Gliomas
GBR 103, 1F
Chair(s)
Jong Bae Park (National Cancer Center, Korea)
11:40-12:00
Dissecting response to treatment in adult patients with a glioma Pre-recording Only
Roel Verhaak (Jackson Laboratory for Genomic Medicine, USA)
12:00-12:20
The epigenetic evolution of gliomas associates with malignant transformation after standard treatment Pre-recording Only
Houtan Noushmehr (Hermelin Brain Tumor Center & Henry Ford Health System, USA)
12:20-12:40
Evolution of Glioblastoma: Proteogenomics aspects in longitudinal study Onsite
Jong Bae Park (National Cancer Center, Korea)
11:40-12:40
Education Session 6
Clinical Trials for Adult Brain Tumors
GBR 104+105, 1F
Chair(s)
Jaeho Cho (Severance Hospital, Yonsei University, Korea)
11:40-12:00
Updates and Ongoing NRG Oncology/RTOG trials for brain metastases and primary CNS tumors Pre-recording + Live Q&A
Minesh P Mehta (Miami Cancer Institute, USA)
12:00-12:20
Updates & ongoing EORTC trials for primary brain tumors Pre-recording Only
Pim J. French (Erasmus MC Cancer Institute, The Netherlands)
12:20-12:40
Updates and ongoing trials of heavy ion therapy for brain tumors Cancelled
Jiade J. Lu (Shanghai Proton and Heavy Ion Center, China)
13:40-14:40
Education Session 7
Role of Surgery in Malignant Brain Tumors
GBR 101+102, 1F
Chair(s)
Jeong-Hyun Hwang (Kyungpook National University, Korea)
13:40-14:00
Extent of resection threshold in malignant gliomas Pre-recording Only
Nader Sanai (Barrow Neurological Institute, USA)
14:00-14:20
Role of supratotal resection in gliomas Onsite
Jong Hee Chang (Severance Hospital, Yonsei University, Korea)
14:20-14:40
Role of Surgery in Lower-Grade Gliomas Pre-recording Only
Lorenzo Bello (University of Milan, Italy)
13:40-14:40
Education Session 8
Cell of Origin in Glioblastoma
GBR 103, 1F
Chair(s)
Do-hyun Nam (Samsung Medical Center, Sungkyunkwan University, Korea)
13:40-14:00
Spatial & Temporal Surgical Sampling of Glioma: Challenges & Opportunities Pre-recording Only
Colin Watts (University of Birmingham, United Kingdom)
14:00-14:20
Molecular signature of glioblastoma origin site and origin cells Onsite
Seok-Gu Kang (Severance Hospital, Yonsei University, Korea)
14:20-14:40
Glioma, Cell of Origin Pre-recording Only
Luis F. Parada (Memorial Sloan Kettering Cancer Center, USA)
13:40-14:40
Education Session 9
Systemic Treatment for High Grade Glioma
GBR 104+105, 1F
Chair(s)
Yu Jung Kim (Seoul National University, Korea)
13:40-14:00
Systemic Treatment for Recurrent High Grade Gliomas: Current Standard Cancelled
Matthias Preusser (Medical University of Vienna, Austria)
14:00-14:20
Precision Medicine and Targeted Therapy for High Grade Glioma Pre-recording + Live Q&A
Mark Rosenthal (Peter MacCallum Cancer Centre, Australia)
14:20-14:40
Updates on Immunotherapy for High Grade Glioma Pre-recording Only
Antonio Omuro (Yale Brain Tumor Center, Yale University, USA)
14:40-15:40
Education Session 10
Functional Anatomy and Brain Mapping for Brain Tumor Surgery
GBR 101+102, 1F
Chair(s)
Euihyun Kim (Severance Hospital, Yonsei University, Korea)
14:40-15:00
White matter anatomy of the brain Pre-recording Only
Christophe Destrieux (Tours University, France)
15:00-15:20
A Connectomic Atlas of the Human Cerebrum Pre-recording + Live Q&A
Michael E. Sughrue (Prince of Wales Private Hospital, Australia)
15:20-15:40
Clinical management of gliomas at the functional regions of brain Pre-recording + Live Q&A
Chuanlu Jiang (Harbin Medical University, China)
14:40-15:40
Education Session 11
Relationship of Brain Circuit and Glioma
GBR 103, 1F
Chair(s)
Seok-Gu Kang (Severance Hospital, Yonsei University, Korea)
14:40-15:00
Tumor microtubes: drivers of glioma progression and resistance Zoom Live Lecture
Frank Winkler (Heidelberg University and German Cancer Research Center, Germany)
15:00-15:20
Electrical and synaptic integration of glioma into neural circuits Pre-recording + Live Q&A
Michelle Monje (Stanford University, USA)
15:20-15:40
Cellular quiescence and resistance in glioblastoma Pre-recording + Live Q&A
Lachlan Harris (The Francis Crick Institute, United Kingdom)
14:40-15:40
Education Session 12
Management of Chemotherapy Side Effects
GBR 104+105, 1F
Chair(s)
Mark Rosenthal (Peter MacCallum Cancer Centre, Australia)
Seung Ho Yang (The Catholic University of Korea, Korea)
14:40-15:00
Management of Side Effects of Cytotoxic Chemotherapy in Brain Tumor Onsite
Joo Han Lim (Inha University, Korea)
15:00-15:20
Adverse Events of Antiangiogenic Agents and Other Targeted Agents Pre-recording + Live Q&A
Wolfgang Wick (University of Heidelberg, Germany)
15:20-15:40
Immune Related Adverse Events Pre-recording + Live Q&A
John F. de Groot (University of California, San Francisco (UCSF), USA)
16:00-17:00
Education Session 13
Technical Innovations in Brain Tumor Surgery
GBR 101+102, 1F
Chair(s)
Tae Hoon Roh (Ajou University, Korea)
16:00-16:20
Virtual Reality for Neurosurgery Pre-recording Only
Walter Jean (Lehigh Valley Health Network, USA)
16:20-16:40
Smart Cyber Operating Theater (SCOT) for Brain Tumor Surgery Pre-recording + Live Q&A
Yoshihiro Muragaki (Tokyo Women's Medical University, Japan)
16:40-17:00
High-field Intraoperative MRI and Glioma Surgery Pre-recording Only
Michael R. Chicoine (Washington University, USA)
16:00-17:00
Education Session 14
Gut-CNS Axis for Brain Tumor
GBR 103, 1F
Chair(s)
Chul-Kee Park (Seoul National University, Korea)
16:00-16:30
Elucidating the resistance to immunotherapy in brain tumors using a humanized microbiome mouse model Pre-recording Only
Braden C. McFarland (University of Alabama at Birmingham, USA)
16:30-17:00
Gut microbiota alterations affect glioma growth and innate immune cells involved in tumor immunosurveillance in mice Pre-recording Only
Cristina Limatola (Sapienza University, Italy)
16:00-17:00
Education Session 15
Quality of Life and More Among Brain Tumor Patients
GBR 104+105, 1F
Chair(s)
Juhee Cho (Samsung Medical Center, Sungkyunkwan University, Korea)
16:00-16:20
Why should we assess quality of life in adult brain tumor patients? Pre-recording + Live Q&A
Zarnie Lwin (University of Queensland, Australia)
16:20-16:40
Fear of cancer recurrence in adult CNS patients Pre-recording + Live Q&A
Phyllis Butow (The University of Sydney, Australia)
16:40-17:00
Later and long-term effect of pediatric brain tumor treatment Onsite
Jung Lee (Seoul National University, Korea)
16:00-18:00
2022 Annual Meeting of the KSNO
Room 209, 2F
16:00-16:30
Connecting human development, aging and disease using single-cell transcriptomics
Jong-Eun Park (Korea Advanced Institute of Science and Technology (KAIST), Korea)
16:30-17:00
Generation and utility of regionally defined human brain organoids
In-Hyun Park (Yale University, USA)
17:00-17:15
KSNO Scientific Award I - Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma
Jason K. Sa (Korea University College of Medicine, Korea)
17:15-17:30
KSNO Scientific Award II - Spatiotemporal Heterogeneity in Multiparametric Physiologic MRI Is Associated with Patient Outcomes in IDH-Wildtype Glioblastoma
Ji Eun Park (University of Ulsan College of Medicine, Korea)
17:30-17:45
KSNO Scientific Award (BTRT) - Delayed Hyponatremia after Transsphenoidal Surgery for Pituitary Adenomas: A Single Institutional Experience
Yun Gi Hong (Yonsei University College of Medicine, Korea)
17:45-18:00
Award Ceremony
17:00-18:00
Education Session 16
Endoscopic Skull Base Surgery
GBR 101+102, 1F
Chair(s)
Gi-Taek Yee (Gachon University, Korea)
17:00-17:20
Cranial Nerve Preservation in Endoscopic Skull Base Surgery Pre-recording + Live Q&A
Won Kim (University of California, Los Angeles (UCLA), USA)
17:20-17:40
How to manage the complication of endoscopic skull base surgery: Preservation of the vascular structure Pre-recording Only
Masahiro Shin (University of Tokyo, Japan)
17:40-18:00
Optical Principles of Fluorescence-Guidedendoscopic tumor surgery Pre-recording Only
John Lee (University of Pennsylvania, USA)
17:00-18:00
Education Session 17
Glioma Epigenetics: Glioma and Histone Remodeling
GBR 103, 1F
Chair(s)
Young Zoon Kim (Samsung Changwon Hospital, Sungkyunkwan University, Korea)
17:00-17:20
Identification and clinical implications of MET alterations in brain tumor Pre-recording + Live Q&A
Tao Jiang (Capital Medical University, China)
17:20-17:40
RNA interference in glioma biology Pre-recording + Live Q&A
Adelheid Woehrer (Institute of Neurology, Medical University of Vienna, Austria)
17:40-18:00
The Potent Epigenetic Mechanism for Medulloblastoma Suppression Pre-recording Only
MinGyu Lee (The University of Texas MD Anderson Cancer Center, USA)
17:00-18:00
Education Session 18
Advanced Practice Nursing for Patients with Brain Tumors
GBR 104+105, 1F
Chair(s)
Sanghee Kim (Severance Hospital, Yonsei University, Korea)
17:00-17:20
Neuro Oncology Nursing in the UK: raising the bar Pre-recording Only
Ingela Oberg (Addenbrooke’s hospital, Cambridge University, United Kingdom)
17:20-17:40
Professional Practice Model for Advanced Practitioners in Neuro Oncology Pre-recording Only
Christina K. Cone (The Preston Robert Tisch Brain Tumor Center, Duke Center for Brain and Spine Metastasis, USA)
17:40-18:00
Quality of Life in Patients with Pituitary Adenoma and Research Recommendations Pre-recording Only
Min Kyeong Jang (Yonsei University and University of Illinois at Chicago, Korea)
18:00-19:00
Sponsored Symposium 1
Hyundai Pharm
GBR 101+102, 1F
Chair(s)
Jeong Hoon Kim (Asan Medical Center, University of Ulsan, Korea)
18:00-18:30
Application of TachoSil for prevention of CSF leak in brain tumor surgery Onsite
Tae Hoon Roh (Ajou University, Korea)
18:30-19:00
Experience of hemostatic materials in brain tumor surgery Onsite
Wan-Soo Yoon (The Catholic University of Korea, Korea)
18:00-19:00
Sponsored Symposium 2
MSD Korea
GBR 103, 1F
18:00-19:00
Optimal Treatment with Temozolomide and Treatment Experience in Glioblastoma Multiforme Onsite
Jong Hee Chang (Severance Hospital, Yonsei University, Korea)
18:00-19:00
ASNO Reformation Ceremony
GBR 104+105, 1F
18:00-18:02
Opening Remarks
Secretary-Treasurer, ASNO
18:03-18:06
Welcome Address
President, ASNO 
18:07-18:17
Introduction of ASNO History
Rakesh Jalali 
18:18-18:23
Introduction of Reformation Process
Se-Hyuk Kim 
18:24-18:35
Congratulatory Remarks
Yong-Kil Hong / President, WFNOS
Tracy Batchelor / President, SNO
Matthias Preusser / President, EANO
18:36-18:39
Introduction of New Officers
President, ASNO
18:40-18:48
Introduction of New Membership System
Chair, Membership Committee
18:49-18:57
Future Plans
President-elect, ASNO
18:58-19:00
Closing Remarks
Secretary-Treasurer, ASNO
07:00-08:00
Opening Symposium 1
Raising the Understanding of Stemness, Plasticity and Hierarchy in CNS Malignancies
Auditorium, 3F
Chair(s)
Do-Hyun Nam (Samsung Medical Center, Sungkyunkwan University, Korea)
07:00-07:30
Metabolic heterogeneity of glioma stem cells Pre-recording + Live Q&A
Hideyuki Saya (Keio University, Japan)
07:30-08:00
Discovery and Understanding of Oncogenic Fusion Genes in Ependymoma Pre-recording + Live Q&A
Daisuke Kawauchi (National Center of Neurology and Psychiatry, Japan)
07:00-08:00
Opening Symposium 2
Awake Craniotomy for Brain Tumors
GBR 101+102, 1F
Chair(s)
Jong Hee Chang (Severance Hospital, Yonsei University, Korea)
07:00-07:30
Language and cognitive mapping in lower-grade glioma surgery: about over 1100 awake procedures Pre-recording Only
Hugues Duffau (Montpellier University Medical Center, France)
07:30-08:00
Awake craniotomy for insula gliomas Pre-recording Only
Jinsong Wu (Fudan University, China)
07:00-08:00
Opening Symposium 3
Neuro-oncologic Imaging: Metabolic and Biomarker Imaging
GBR 103, 1F
Chair(s)
Ji Eun Park (Asan Medical Center, University of Ulsan, Korea)
07:00-07:20
Brain tumors—Imaging surrogates of molecular genetic signature Pre-recording + Live Q&A
Soonmee Cha (University of California, San Francisco (UCSF), USA)
07:20-07:40
Imaging updates for genetic mutation and tissue proliferation (2HG-MR spectroscopy, amide proton transfer imaging, and AI) Onsite
Ji Eun Park (Asan Medical Center, University of Ulsan, Korea)
07:40-08:00
Application of Arterial Spin Labeling in Brain Tumor Onsite
Tae Jin Yun (Seoul National University, Korea)
07:00-08:00
Opening Symposium 4
New Horizon of Pediatric Glial Tumor
GBR 104+105, 1F
Chair(s)
Hye Lim Jung (Sungkyunkwan University, Korea)
07:00-07:20
Novel Treatment Strategies of Pediatric LGG Pre-recording Only
Jason Fangusaro (Children’s Healthcare of Atlanta, Emory University, USA)
07:20-07:40
Druggable targets in pediatric and adolescent HGG Pre-recording Only
Chris Jones (The Institute of Cancer Research, United Kingdom)
07:40-08:00
DIPG in children and adolecents Pre-recording Only
Chris Jones (The Institute of Cancer Research, United Kingdom)
08:10-08:25
Opening Ceremony
Auditorium, 3F
08:10-08:15
Welcome Address
Yong-Kil Hong
08:15-08:20
Congratulatory Address
Martin van den Bent
08:20-08:25
Congratulatory Address
Patrick Y. Wen
08:25-08:55
Keynote Lecture EANO
Auditorium, 3F
Chair(s)
Yong-Kil Hong (Hallym University, Korea)
08:25-08:55
Immune targeting of driver mutations in glioma Pre-recording + Live Q&A
Michael Platten (University Hospital Mannheim, Heidelberg University, Germany)
08:55-10:15
Plenary Session 2
Brain Circuit and Glioma
Auditorium, 3F
Chair(s)
Seok-Gu Kang (Severance Hospital, Yonsei University, Korea)
08:55-09:35
Communicating networks in brain tumors, and their clinical implications Zoom Live Lecture
Frank Winkler (Heidelberg University and German Cancer Research Center, Germany)
09:35-10:15
Neuronal regulation of glioma progression Pre-recording + Live Q&A
Michelle Monje (Stanford University, USA)
10:15-11:30
WFNOS 2022 Top 10 Session 1
Auditorium, 3F
Chair(s)
Choong Hyun Kim (Hanyang University, Korea)
10:15-10:30
A phase I first-in-human trial with local application of CAR-NK cells targeting HER2 in patients with recurrent glioblastoma (CAR2BRAIN): Results of the dose-escalation cohort Pre-recording + Live Q&A
Michael C Burger (Goethe University Hospital, Germany)
10:30-10:45
Extra-chromosomal DNA (ecDNA) do not necessarily cluster or interact with condensates in Glioblastoma Stem Cells Pre-recording + Live Q&A
Karin Purshouse (University of Edinburgh, United Kingdom)
10:45-11:00
Inhibition of mutant IDH1 increases T-cell infiltration and synergizes with immune checkpoint inhibition in a humanized glioma mouse model Pre-recording + Live Q&A
Khwab Sanghvi (German Cancer Research Center (DKFZ), Germany)
11:00-11:15
Tirabrutinib, a second-generation BTK inhibitor in relapsed and refractory primary CNS lymphoma: A single institute study Pre-recording Only
Kazuhiko Mishima (Saitama Medical University International Medical Center, Japan)
11:15-11:30
Novel Patient-Derived Xenograft and Cell Line models for Therapeutic Screening in NF2-associated Schwannoma Pre-recording + Live Q&A
Fu Zhao (Beijing Tiantan Hospital, China)
11:50-12:50
Luncheon Seminar 1
Circumscribed Glioma, Glioneuronal Tumor and Ependymoma
GBR 101+102, 1F
Chair(s)
Se Hoon Kim (Severance Hospital, Yonsei University, Korea)
11:50-12:10
Circumscribed Gliomas Zoom Live Lecture
Tarik Tihan (University of California, San Francisco (UCSF), USA)
12:10-12:30
Glioneuronal Tumor Pre-recording + Live Q&A
Takashi Komori (Tokyo Metropolitan Neurological Hospital, Japan)
12:30-12:50
Ependymoma Pre-recording Only
Torsten Pietsch (University of Bonn, Germany)
11:50-12:50
Luncheon Seminar 2
Updates on RANO Criteria for Response Evaluation
GBR 103, 1F
Chair(s)
Ji Eun Park (Asan Medical Center, University of Ulsan, Korea)
11:50-12:10
RANO Criteria for High Grade and Low Grade Gliomas Pre-recording Only
Eudocia Q Lee (Harvard Medical School, USA)
12:10-12:30
RANO Criteria for Brain Metastases and Leptomeningeal Metastases Pre-recording Only
Hidefumi Aoyama (Hokkaido University, Japan)
12:30-12:50
Neurologic Assessment in Neuro-Oncology (NANO) Scale Pre-recording Only
Enrico Franceschi (The Institute of Neurological Sciences of Bologna (ISNB), Italy)
11:50-12:50
Luncheon Seminar 3
Re-evaluating SRS for High Grade Glioma
GBR 104+105, 1F
Chair(s)
Sun-il Lee (Inje University, Korea)
11:50-12:10
Stereotactic Radiosurgery with Temozolomide for Newly Diagnosed Glioblastoma: Pros and Cons Pre-recording Only
Antonio Omuro (Yale Brain Tumor Center, Yale University, USA)
12:10-12:30
Advances in adjuvant and salvage SRS Pre-recording + Live Q&A
Yoshua Esquenazi (University of Texas Health Science Center, USA)
12:30-12:50
Novel treatments combined with SRS Pre-recording + Live Q&A
Frank Anton Giordano (University Medical Center Mannheim, Germany)
13:10-14:40
Keynote & Scientific Session 1
Gliomas: Molecular Pathology
Auditorium, 3F
Chair(s)
Sung-Hye Park (Seoul National University, Korea)
Jason Huse (University of Texas, USA)
13:10-13:30
The 2021 WHO Classification of CNS Tumors Pre-recording Only
David Louis (Harvard Medical School, USA)
13:30-13:40
Molecular characterization of adult cerebellar glioblastomas identifies distinct prognostic subgroups Pre-recording Only
Thiebaud Picart (Lyon University Hospital, France)
13:40-13:50
Low Expression of DYNLT3 Predicts better prognosis for Female Glioblastoma Patients Pre-recording Only
Yuanjun Hu (Sun Yat-sen University Cancer Center, China)
13:50-14:00
FXYD2 mRNA expression represents a new independent factor that affects survival of glioma patients and predicts chemosensitivity of patients to temozolomide Pre-recording Only
Zhou Kaijia (Fujian Cancer Hospital, China)
14:00-14:10
PDGFRA amplification is a significant prognostic marker in patients with IDH wild-type glioblastoma multiforme Pre-recording Only (Q&A attendance not confirmed yet)
Koji Yoshimoto (Kagoshima University, Japan)
14:10-14:20
Comprehensive molecular subgrouping of pleomorphic xanthoastrocytomas (PXA) Pre-recording Only
Prerana Jha (Karkinos Healthcare, India)
14:20-14:30
High frequency of PDGFRA and MUC family gene mutations in diffuse hemispheric glioma, H3 G34-mutant: A glimmer of hope? Pre-recording Only
Wanming Hu (Sun Yat-sen University Cancer Center, China)
14:30-14:40
Molecular and clinical features of patients with glioblastoma treated with targeted therapy at Johns Hopkins Medicine Pre-recording + Live Q&A
Michael Chang (Johns Hopkins University, USA)
13:10-14:40
Keynote & Scientific Session 2
Gliomas: Surgery and Clinical Research
GBR 101+102, 1F
Chair(s)
Chae-Yong Kim (Seoul National University, Korea)
Mitchel Berger (University of California, San Francisco (UCSF), USA)
13:10-13:30
The rationale and methods to achieve a safe, maximal glioma resection Zoom Live Lecture
Mitchel Berger (University of California, San Francisco (UCSF), USA)
13:30-13:40
Impact of First-Line Surgical Treatment of Low-Grade Glioma on Mental Health Disorder Onset Pre-recording + Live Q&A
Debarati Bhanja (Penn State College of Medicine, USA)
13:40-13:50
Incorporating diffusion- and perfusion-weighted MRI radiomics to clinical features improves prediction of survival in patients with lower-grade gliomas Onsite
Chae Jung Park (Yongin Severance Hospital, Yonsei University, Korea)
13:50-14:00
Prognostic Relevance of Adding Radiomics to the WHO 2021 Updates for IDH-Wildtype Lower-grade Gliomas with Known EGFR Amplification and TERT Promoter Mutation Status Onsite
Yae Won Park (Severance Hospital, Yonsei University, Korea)
14:00-14:10
Systematic Review - Time to Malignant Transformation in Low Grade Gliomas: Predicting a catastrophic event with clinical, neuroimaging and molecular markers Pre-recording Only
Zabina Satar (The National Hospital, University College London, United Kingdom)
14:10-14:20
Anlotinib alone or in combination with temozolomide in recurrent high-grade glioma: a retrospective analysis Pre-recording Only
Qunying Yang (Sun Yat-Sen University Cancer Center, China)
14:20-14:30
Mood disorder, Health Related Quality of Life and Sexual life disturbances in glioma patients: prevalence and putative factors Pre-recording Only
Guglielmo Puglisi (University of Milan, Italy)
13:10-14:40
Keynote & Scientific Session 3
Gliomas: Immunotherapy and Uncommon Tumors
GBR 103, 1F
Chair(s)
Dong-Sup Chung (The Catholic University of Korea, Korea)
13:10-13:30
Target combine with immunotherapy: Is a hope for glioma treatment? Pre-recording + Live Q&A
Zhong-Ping Chen (Sun Yat-sen University, China)
13:30-13:40
A glioneuronal tumor with CLIP2-MET fusion Onsite
Tamrin Chowdhury (Seoul National University, Korea)
13:40-13:50
Inhibition of MUC1 exerts cell-cycle arrest and telomerase suppression in glioblastoma cells Onsite
Youngbeom Seo (Yeungnam University Medical Center, Korea)
13:50-14:00
Intracranial solitary fibrous tumor/hemangiopericytoma: tumor reclassification and assessment of treatment outcome via the 2016 WHO classification Onsite
Dongwon Shin (Asan Medical Center, University of Ulsan, Korea)
14:00-14:10
Sporadic Solid/cystic Hemangioblastomas in the Cerebellum: Retrospective Study in a Single Center Pre-recording Only
Xia Haijian (The First Affiliated Hospital of Chongqing Medical University, China)
14:10-14:20
Apparent diffusion coefficient as a prognostic factor in clival chordoma Onsite
Hyeong Cheol Oh (Gangnam Severance Hospital, Yonsei University, Korea)
14:20-14:30
Posterior fossa ependymomas: Evaluation of H3K27me3 expression and 1q gains Pre-recording Only
Janani Amudhakumar (Tata Memorial Centre, India)
14:30-14:40
Suggestions for escaping the Dark Ages for pediatric diffuse intrinsic pontine glioma treated with radiotherapy: analysis of prognostic factors from the National multicenter study Onsite
Hyun Ju Kim (Gachon University Gil Medical Center, Korea)
13:10-14:40
Keynote & Scientific Session 4
Gliomas: Cancer Stem Cell
GBR 104+105, 1F
Chair(s)
Jinquan Cai (The Second Affiliated Hospital of Harbin Medical University, China)
Sara G.M. Piccirillo (University of New Mexico, USA)
Dokyoung Kim (Kyung Hee University, Korea)
13:10-13:30
Dissecting glioblastoma by single cell RNA-seq Pre-recording + Live Q&A
Itay Tirosh (Weizmann Institute of Science, Israel)
13:30-13:40
Biological characteristics comparison of glioblastoma tumorsphere obtained from the fresh and cryopreservation sample Onsite
Min Kyun Na (Hanyang University Medical Center, Korea)
13:40-13:50
Loss of PrPC modulates expression and localization of stemness markers in Glioblastoma stem-like cells Pre-recording + Live Q&A
Mariana Brandao Prado (Institute of Medical Sciences, University of Sao Paulo, Brazil)
13:50-14:00
Sema3C Signaling Confers Resistance to Wnt Inhibition in Glioblastoma Pre-recording + Live Q&A
Jennifer Yu (Cleveland Clinic, USA)
14:00-14:10
Silencing of Gli2 suppresses tumorigenicity in glioblastoma stem cells derived from a de novo murine brain cancer model Pre-recording Only
Seisuke Tanigawa (Kyoto Pharmaceutical University, Japan)
14:10-14:20
The specific FGFR inhibitor INCB054828 (Pemigatinib) radiosensizes unmethylated MGMT glioblastoma cells and Glioblastoma stem cells Pre-recording Only
Elizabeth Cohen-Jonathan Moyal (Institut Claudius Regaud, IUCT-Oncopole, France)
14:20-14:30
Local tumor after surgical resection arises from subventricular zone via CXCL12/CXCR4 axis in the glioblastoma Onsite
Xue Li (Seoul National University Hospital, Korea)
14:40-15:40
Symposium 1
Featured Clinical Trials for Newly Diagnosed Glioblastoma
Auditorium, 3F
Chair(s)
Hwan Jung Yun (Chungnam National University, Korea)
14:40-15:00
Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA–09): a randomised, open-label, phase 3 trial Pre-recording + Live Q&A
Wolfgang Wick (University of Heidelberg, Germany)
15:00-15:20
Predictive biomarkers for bevacizumab response in newly-diagnosed glioblastoma Pre-recording + Live Q&A
Ryo Nishikawa (Saitama Medical University, Japan)
15:20-15:40
Challenges and opportunities for drug development in newly diagnosed GBM Zoom Live Lecture
Roger Stupp (Northwestern University, USA)
14:40-15:40
Symposium 2
Beyond the Limits of Endoscopic Skull Base Surgery
GBR 101+102, 1F
Chair(s)
Doo-Sik Kong (Samsung Medical Center, Sungkyunkwan University, Korea)
14:40-15:00
360 degree approaches to the skull base tumors Pre-recording only
James Liu (Rutgers University, USA)
15:00-15:20
Endoscopic endonasal surgery for skull base tumors Pre-recording + Live Q&A
Calvin Mak (Queen Elizabeth Hospital, Hong Kong)
15:20-15:40
Endoscopic endonasal supraoptic and infraoptic approaches for the complex “para-suprasellar” lesions:surgical anatomy, technique nuances, and case series Pre-recording + Live Q&A
Tao Hong (The First Affiliated Hospital of Nanchang University, China)
14:40-15:40
Symposium 3
Role of Epigenetic Alteration in Cancer
GBR 103, 1F
Chair(s)
Young Zoon Kim (Samsung Changwon Hospital, Sungkyunkwan University, Korea)
14:40-15:00
Unraveling epigenetic and metabolic cross-talk in DIPG (diffuse intrinsic pontine glioma) Onsite
Chan Chung (Daegu Gyeongbuk Institute of Science and Technology (DGIST), Korea)
15:00-15:20
Epigenetic regulation in glioblastomas Pre-recording Only
Antonio Iavarone (Columbia University , USA)
15:20-15:40
Epigenetic alterations defines progression in a subset of IDH mutant gliomas Pre-recording Only
Houtan Noushmehr (Hermelin Brain Tumor Center & Henry Ford Health System, USA)
14:40-15:40
Symposium 4
Relapsed Medulloblastoma
GBR 104+105, 1F
Chair(s)
Hyeon Jin Park (National Cancer Center, Korea)
14:40-15:00
Embryonal brain tumors – Challenges in Treatment versus Science Pre-recording + Live Q&A
Wan-Yee Teo (Duke-NUS Medical School, Singapore)
15:00-15:20
Salvage chemotherapy of relapsed medulloblastoma Pre-recording + Live Q&A
Keita Terashima (National Center for Child Health and Development, Japan )
15:20-15:40
The role of radiotherapy in relapsed medulloblastoma Onsite
Do Hoon Lim (Samsung Medical Center, Sungkyunkwan University, Korea)
16:00-17:00
Symposium 5
Featured Clinical Trials for Recurrent Glioblastoma
Auditorium, 3F
Chair(s)
Riccardo Soffietti (University of Turin, Italy)
Yun-Gyoo Lee (Samsung Medical Center, Sungkyunkwan University, Korea)
16:00-16:30
INTELLANCE 2/EORTC 1410 randomized phase II study of Depatux-M alone and with temozolomide vs temozolomide or lomustine in recurrent EGFRamplified glioblastoma Pre-recording + Live Q&A
Martin van den Bent (Erasmus MC Cancer Institute, The Netherlands)
16:30-17:00
Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systematic immune responses in recurrent glioblastoma Pre-recording Only
Patrick Wen (Harvard Medical School, USA)
16:00-17:00
Symposium 6
Advance in Anti-glioma Strategy
GBR 101+102, 1F
Chair(s)
Jung-Il Lee (Samsung Medical Center, Sungkyunkwan University, Korea)
16:00-16:20
Gene-drug screening for precision neuro-oncology Onsite
Do-hyun Nam (Samsung Medical Center, Sungkyunkwan University, Korea)
16:20-16:40
Energy and Protein Starvation to Circumvent Glioma Heterogeneity Pre-recording + Live Q&A
Vinay Puduvalli (The University of Texas MD Anderson Cancer Center, USA)
16:40-17:00
The role of extrachromosomal DNA amplifications in glioblastoma Pre-recording Only
Roel Verhaak (Jackson Laboratory for Genomic Medicine, USA)
16:00-17:00
Symposium 7
Neuro-oncologic Imaging: Microenvironmental Imaging
GBR 103, 1F
Chair(s)
Seung-Koo Lee (Severance Hospital, Yonsei University, Korea)
16:00-16:20
Evaluation of tumor habitat: Application of Radiomic Methods in Neuro-Oncology Pre-recording Only
Raymond Huang (Harvard Medical School, USA)
16:20-16:40
Imaging spatiotemporal heterogeneity of treated glioblastoma: longitudinal assessment of subregional habitats using multiparametric MRIs Pre-recording Only
Ho Sung Kim (Asan Medical Center, University of Ulsan, Korea)
16:40-17:00
Understanging microenviroment of brain tumors using imaging modatlities Onsite
Seung Hong Choi (Seoul National University, Korea)
16:00-17:00
Symposium 8
Familial Predisposition of CNS Tumors
GBR 104+105, 1F
Chair(s)
Chul-Kee Park (Seoul National University, Korea)
16:00-16:20
Racial differences in glioma risk Pre-recording + Live Q&A
Melissa Bondy (Stanford University, USA)
16:20-16:40
Genetic predisposition for gliomagenesis Pre-recording Only
Robert B. Jenkins (Mayo Clinic, USA)
16:40-17:00
Genetic and metabolic risk factors for glioma development Pre-recording + Live Q&A
Beatrice Melin (Umea University, Sweden)
17:00-18:30
Keynote & Scientific Session 5
Gliomas: Signaling, Microenvironment
Auditorium, 3F
Chair(s)
Youn Soo Lee (The Catholic University of Korea, Korea)
Lachlan Harris (The Francis Crick Institute, United Kingdom)
17:00-17:20
Practical approaches towards CNS tumor diagnosis using methylation profiling and machine learning Pre-recording Only
Kenneth Aldape (National Cancer Institute, Center for Cancer Research, Canada)
17:20-17:30
Distinct invasive pathways are driven by major oncogenetic drivers in glioblastoma Pre-recording + Live Q&A
Emil Rosen (Uppsala University, Sweden)
17:30-17:40
Breaching the blood brain barrier (BBB) by Tumor Treating Fields (TTFields) could be a novel chemotherapeutic delivery strategy Pre-recording + Live Q&A
Carsten Hagemann (University Hospital Würzburg, Germany)
17:40-17:50
Single-cell transcriptomic and epigenomic immune landscape of human gliomas Pre-recording Only
Krishna Bhat (The University of Texas MD Anderson Cancer Center, USA)
17:50-18:00
Inhibition of PI3K restores cancer cell sensitivity to Tumor Treating Fields (TTFields) Pre-recording + Live Q&A
Anat Klein-Goldberg (Novocure, Israel)
18:00-18:10
Identification of growth hormone receptor as a relevant target for precision medicine in low-EGFR expressing glioblastoma Pre-recording + Live Q&A
Irma Segoviano Vilchis (ICM Institute for Brain and Spinal Cord, France)
18:10-18:20
Transcriptomic analysis reveals novel Tumour Microenvironment subtypes in IDH wildtype Glioblastoma Pre-recording Only
Kieron White (Royal College of Surgeons, Ireland)
18:20-18:30
Proteomic analysis predicts anti-angiogenic resistance in the recurred IDH-wild type glioblastoma Onsite
Hanwool Jeon (Asan Medical Center, University of Ulsan, Korea)
17:00-18:30
Keynote & Scientific Session 6
Gliomas: Surgery
GBR 101+102, 1F
Chair(s)
Yoshihiro Muragaki (Tokyo Women's Medical University, Japan)
Wan-Soo Yoon (The Catholic University of Korea, Korea)
17:00-17:20
Importance of functional anatomy in glioma surgery Pre-recording + Live Q&A
Marcos Maldaun (The Syrian-Lebanese Hospital, Brazil)
17:20-17:30
Deep white matter portion of dorsal superior longitudinal fascicle is a critical region for preservation of visuospatial cognition during glioma surgery Pre-recording + Live Q&A
Mitsutoshi Nakada (Kanazawa University, Japan)
17:30-17:40
Resection of supplementary motor area gliomas: revisiting supplementary motor syndrome and the role of the frontal aslant tract Pre-recording + Live Q&A
Andrew Gogos (St Vincents Hospital, Australia)
17:40-17:50
Preservation of language function by mapping arcuate fasciculus using intraoperative cortico-cortical evoked potential under general anesthesia in glioma surgery Cancelled
Kyungmin Kim (Seoul National University Hospital, Korea)
17:50-18:00
Development of novel topical fluorescent probe for intraoperative rapid detection of glioma Pre-recording + Live Q&A
Shota Tanaka (The University of Tokyo, Japan)
18:00-18:10
Patterns of recurrence according to the extent of resection in patients with IDH-wildtype glioblastoma: a retrospective study Onsite
Jihwan Yoo (Gangnam Severance Hospital, Yonsei University, Korea)
18:10-18:20
Stereotactic biopsy for adult brainstem lesions: a surgical approach and its diagnostic value according to the 2016 World Health Organization Classification Onsite
In-Ho Jung (Severance Hospital, Yonsei University, Korea)
17:00-18:30
Keynote & Scientific Session 7
Gliomas: Novel therapeutics, Radiotherapy, and Machine Learning
GBR 103, 1F
Chair(s)
Chan Woo Wee (Seoul National University BORAMAE Medical Center, Korea)
17:00-17:20
The use of skull implantable ultrasound for delivery of chemotherapy, results from a phase 1 clinical trial Zoom Live Lecture
Adam Sonabend (Northwestern University Feinberg, USA)
17:20-17:30
Human bone-marrow derived mesenchymal stromal cells increase glioblastoma radioresistance Pre-recording + Live Q&A
Maren Strack (University of Freiburg, Germany)
17:30-17:40
Efficacy of Whole-Ventricular Radiotherapy in Patients Undergoing Maximal Tumor Resection for Glioblastomas Involving the Ventricle Onsite
Hong In Yoon (Yonsei Cancer Center, Yonsei University, Korea)
17:40-17:50
Deep Learning Radiomics to Predict PTEN Mutation Status From Magnetic Resonance Imaging in Patients With Glioma Pre-recording Only
Hongyu Chen (Sun Yat-sen University Cancer Center, China)
17:50-18:00
Interpretable machine learning model for prediction of prognosis in patients with glioblastoma Pre-recording Only
Wonmo Sung (The Catholic University of Korea, Korea)
18:00-18:10
Volumetric change in brain cortex and gray matter after radiotherapy in glioma patients detected with longitudinal magnetic resonance imaging Onsite
Hye In Lee (Seoul National University Hospital, Korea)
18:10-18:20
Quantitative Cerebral Blood Volume Images synchesis from Standard MRI Using Generative Adversarial Network: A Single Center Dataset of 756 Scans Pre-recording + Live Q&A
Yingchao Liu (Provincial Hospital Affiliated to Shandong First Medical University, China)
17:00-18:30
Keynote & Scientific Session 8
Uncommon CNS Tumors
GBR 104+105, 1F
Chair(s)
Chuanlu Jiang (Harbin Medical University, China)
Sang Woo Song (Asan Medical Center, University of Ulsan, Korea)
17:00-17:20
Thromboembolism in patients with brain tumours Pre-recording Only
James Perry (University of Toronto, Canada)
17:20-17:30
Questionnaire survey regarding working condition of the members belongs to the Japan Society for Neuro-Oncology (JSNO) by the Gender Equality and Diversity Committee of the JSNO 2021 Pre-recording + Live Q&A
Takamitsu Fujimaki (Gender Equality and Diversity Committee of the Japan Society for Neuro-oncology, Japan)
17:30-17:40
Primary brain tumor research productivity in Southeast Asia and its association with socioeconomic determinants and burden of disease Pre-recording + Live Q&A
Mark Willy Mondia (Philippine General Hospital, Philippines)
17:40-17:50
Perception of Uncertainty Concerning Illness and Coping Styles among Parents of Children with Central Nervous System Tumors: a Correlation Analysis Pre-recording Only
Lan Bai (Sun Yat-sen University Cancer Center, China)
17:50-18:00
Treatment of 148 cases of intracranial germ cell tumors, dynamic monitoring of lymphocyte subsets and related prognosis Pre-recording + Live Q&A
Hairong Wang (Sun Yat-sen University Cancer Center, China)
18:00-18:10
Rare germline variants in the tumor suppressor gene CDH1 in glioma families and gastric cancer families with brain tumors Pre-recording + Live Q&A
Ruthild G. Weber (Hannover Medical School, Germany)
18:10-18:20
TTF-1: a well-favoured addition to the immunohistochemistry armamentarium as a diagnostic marker of SEGA Pre-recording + Live Q&A
Rimlee Dutta (All India Institute of Medical Sciences, India)
18:30-19:30
Sponsored Symposium 3
Tumor Treating Fields: A Force for Change (Novocure GmbH)
GBR 101+102, 1F
Chair(s)
David Tran (University of Florida, USA)
18:30-18:35
Welcome and introduction Pre-recording Only
David Tran (University of Florida, USA)
18:35-18:45
Disruptive Technology: How do TTFields work Pre-recording Only
Michael D. Story (University of Texas, USA)
18:45-19:00
Optune®: An Established treatment for patients with glioblastoma Pre-recording Only
David Tran (University of Florida, USA)
19:00-19:15
Clinical insights: Expert perspectives on the use of Optune® in glioblastoma Pre-recording Only
Michael Sabel (University Hospital Düsseldorf, Germany)
19:15-19:25
Optune® in the real-world: The patient experience Pre-recording Only
Patient Ambassador
19:25-19:30
Q&A, Summary and close Zoom Live Lecture
David Tran (University of Florida, USA)
18:30-19:30
Sponsored Symposium 4
The Art of Preventing Bleeding during Neurosurgery (Baxter International Inc.)
GBR 103, 1F
Chair(s)
Se-Hyuk Kim (Ajou University, Korea)
18:35-19:00
How to Survival from Bleeding- the Real Enemy is Hiding behind Tumors Onsite
Seung Ho Yang (The Catholic University of Korea, Korea)
19:00-19:25
Evolution of Topical Hemostats and Sealants: “RIGHT PRODUCT FOR RIGHT BLEED” Pre-recording + Live Q&A
Raghavendra Mayya (Baxter Advanced Surgery, APAC, Singapore)
18:30-19:30
Sponsored Symposium 5
Dawonmedax Co.,ltd
GBR 104+105, 1F
Chair(s)
Woo-Kyung Kim (Gachon University, Korea)
18:35-18:50
Development of Proton LINAC based Boron Neutron Capture Therapy (BNCT) System in Korea Onsite
Hyo Jung Seo (Dawonmedax Co.,ltd, Korea)
18:50-19:10
Clinical usefulness of BNCT in neuro-oncology: case review Zoom Live Lecture
Shin-Ichi Miyatake (Osaka Medical College, Japan)
19:10-19:30
A Multi-centered, Open, Exploratory, Phase 1/2a Clinical Trial in High-grade Glioma: Trial Protocol Onsite
Gi-Taek Yee (Gachon University, Korea)
07:00-08:00
Opening Symposium 5
Over the Barrier for Meningioma
Auditorium, 3F
Chair(s)
Bong Jin Park (Kyung Hee University, Korea)
07:00-07:20
Genomic landscape of meningiomas Pre-recording + Live Q&A
Wenya Linda Bi (Harvard Medical School, USA)
07:20-07:40
A clinically applicable integrative molecular classification of meningiomas Zoom Live Lecture
Gelareh Zadeh (Princess Margaret Cancer Centre, University Health Network, Canada)
07:40-08:00
Molecular mechanisms for radiation resistance in aggressive meningiomas Zoom Live Lecture
Albert Kim (Washington University, USA)
07:00-08:00
Opening Symposium 6
Integrative Management of Brain Metastasis
GBR 101+102, 1F
Chair(s)
Se-Hoon Lee (Sungkyunkwan University, Korea)
07:00-07:20
Genomic identification of therapeutic targets in brain metastasis Pre-recording + Live Q&A
Priscilla K. Brastianos (Harvard Medical School, USA)
07:20-07:40
Advances in brain metastasis models Onsite
Seung Ho Yang (The Catholic University of Korea, Korea)
07:40-08:00
Systemic therapy in the management of brain metastasis Pre-recording Only
Michael Weller (University Hospital Zurich, Switzerland)
07:00-08:00
Opening Symposium 7
Biomedical Engineering Approach for Brain Tumors
GBR 103, 1F
Chair(s)
YongTae Kim (Georgia Institute of Technology, USA)
07:00-07:20
3D cell printed Patient-specific Human-glioblastoma-on-a-chip Zoom Live Lecture
Dong-Woo Cho (Pohang University of Science and Technology (POSTECH), Korea)
07:20-07:40
Engineered biomimetic nanoparticle for the treatment of sonic hedgehog medulloblastoma Onsite
YongTae Kim (Georgia Institute of Technology, USA)
07:40-08:00
3D tumor chip for glioblastoma Zoom Live Lecture
Hak-Joon Sung (Yonsei University, Korea)
07:00-08:00
Opening Symposium 8
CNS Germ Cell Tumor 
GBR 104+105, 1F
Chair(s)
Hyeon Jin Park (National Cancer Center, Korea)
07:00-07:20
Surgical management for CNS GCTs Onsite
Seung-Ki Kim (Seoul National University, Korea)
07:20-07:40
Optimization of radiotherapy technique, dose, and field for CNS GCTs Pre-recording + Live Q&A
Derek S. Tsang (Princess Margaret Cancer Centre, University Health Network, Canada)
07:40-08:00
Recent updates in chemotherapy regimens for pediatric CNS GCTs Pre-recording + Live Q&A
Keita Terashima (National Center for Child Health and Development, Japan )
08:25-08:55
Keynote Lecture SNO
Auditorium, 3F
Chair(s)
Youn Soo Lee (The Catholic University of Korea, Korea)
08:25-08:55
A molecular taxonomy for meningiomas Pre-recording + Live Q&A
Farshad Nassiri (University of Toronto, Canada)
08:55-10:15
Plenary Session 3
Auditorium, 3F
Chair(s)
Se-Hyuk Kim (Ajou University, Korea)
08:55-09:35
2021 WHO classification Pre-recording Only
David Capper (Charité University, Germany)
09:35-10:15
CNS border lymphatics and immune cells Onsite
Gou Young Koh (Center for Vascular Research, Institute for Basic Science, Korea)
10:15-11:30
WFNOS 2022 Top 10 Session 2
Auditorium, 3F
Chair(s)
Jeong Hoon Kim (Asan Medical Center, University of Ulsan, Korea)
10:15-10:30
Phase 2 study of pembrolizumab plus TTFields plus temozolomide in patients with newly diagnosed glioblastoma (2-THE-TOP) Pre-recording + Live Q&A
David Tran (University of Florida, USA)
10:30-10:45
Identification of CD317 as a novel target for chimeric antigen receptor (CAR)-based immunotherapy for glioblastoma Pre-recording + Live Q&A
Patrick Roth (University Hospital Zurich, Switzerland)
10:45-11:00
Differential YAP/TAZ activity in human glioblastoma tumorspheres as a potential biomarker Onsite
Euihyun Kim (Severance Hospital, Yonsei University, Korea)
11:00-11:15
Dissecting intra-tumoral heterogeneity in meningiomas on single cell level unveils distinct tumor subpopulations and a differential tumor microenvironment between meningioma subgroups Pre-recording Only
Christina Blume (German Cancer Research Center (DKFZ), Germany)
11:15-11:30
Characterizing and Targeting the Molecular and Cellular Vulnerabilities of Brain Metastasis Pre-recording + Live Q&A
Jason Huse (The University of Texas MD Anderson Cancer Center, USA)
11:50-12:50
Luncheon Seminar 4
Next Generation of Precision Medicine for Brain Tumors
GBR 101+102, 1F
Chair(s)
Jong Bae Park (National Cancer Center, Korea)
11:50-12:10
Classification and targeting of the functional states of glioma Pre-recording Only
Antonio Iavarone (Columbia University , USA)
12:10-12:30
Actionable targets in diffuse IDHwt gliomas Pre-recording Only
Marc Sanson (Sorbonne University, France)
12:30-12:50
Impact of molecular-genetic crowding on clonal evolution of glioma Pre-recording + Live Q&A
Atsushi Natsume (Nagoya University, Japan)
11:50-12:50
Luncheon Seminar 5
Multidisciplinary Treatment of Primary CNS Lymphoma
GBR 103, 1F
Chair(s)
Do Hoon Lim (Samsung Medical Center, Sungkyunkwan University, Korea)
11:50-12:10
Induction chemotherapy and high-dose chemotherapy with autologous stem cell rescue Onsite
Jeong-Ok Lee (Seoul National University Bundang Hospital, Korea)
12:10-12:30
Role of Whole Brain Radiation Therapy (WBRT) and its future Pre-recording + Live Q&A
Richard W. Tsang (Princess Margaret Cancer Centre, University Health Network, Canada)
12:30-12:50
Multidisciplinary treatment of primary CNS lymphoma (PCNSL)- Neurotoxicity and QOL Zoom Live Lecture
Kheng-Wei Yeoh (National Cancer Centre, Singapore)
11:50-12:50
Luncheon Seminar 6
Updates and On-going Clinical Trials for Pediatric Brain Tumors
GBR 104+105, 1F
Chair(s)
Hyung Soo Choi (Seoul National University, Korea)
11:50-12:10
An update on COG trials for pediatric brain tumors Pre-recording + Live Q&A
Susan Chi (Harvard Medical School, USA )
12:10-12:30
Ongoing Clinical Trials within the Pediatric Brain Tumor (PBTC) Consortium Pre-recording Only
Jason Fangusaro (Children’s Healthcare of Atlanta, Emory University, USA)
12:30-12:50
Updates of particle therapy in pediatric brain tumors Pre-recording + Live Q&A
Rakesh Jalali (Apollo Proton Cancer Centre, India)
13:10-14:40
Keynote & Scientific Session 9
Gliomas: Immuno-Oncology
Auditorium, 3F
Chair(s)
Hye Jin Choi (Yonsei Cancer Center, Yonsei University, Korea)
13:10-13:30
Immunotherapy for glioblastoma Pre-recording + Live Q&A
John S. Yu (Cedars-Sinai Medical Center, USA)
13:30-13:40
Artificial Intelligence-directed, Gene Therapy-based Transdifferentiation of Glioblastoma to Functional Dendritic Cells as Novel Cancer Immunotherapy Pre-recording + Live Q&A
David Tran (University of Florida, USA)
13:40-13:50
Antitumor Immunity of Calcipotriol(1α,25(OH)2 vitamin D3 analogue)-induced CD4 T cell activation in Preclinical Glioma Models Onsite
Shin-Hyuk Kang (Korea University Anam Hospital, Korea)
13:50-14:00
Inhibition of Indoleamine 2,3-Dioxygenase in Glioma-Derived Extracellular Vesicles Pre-recording Only
Megan Bauman (Mayo Clinic, USA)
14:00-14:10
Tumor-specific alternative splicing generates spatially-conserved HLA-binding neoantigen targets detected through integrative transcriptomic and proteomic analyses Pre-recording + Live Q&A
Darwin Kwok (University of California, San Francisco (UCSF), USA)
14:10-14:20
Development of a compartment locked IL-12 version with increased tissue retention and minimal peripheral exposure for local glioblastoma therapy Pre-recording Only
Linda Schellhammer (University of Zurich, Switzerland)
14:20-14:30
Multifaceted transcriptomic and proteomic analyses identified putative alternative splicing-derived cell surface antigens in glioma Pre-recording Only
Takahide Nejo (University of California, San Francisco (UCSF), USA)
14:30-14:40
Predictive Biomarkers for the responsiveness to Autologous Activated Killer cell immunotherapy in recurrent Glioblastomas Onsite
Jaejoon Lim (Bundang CHA General Hospital, Korea)
13:10-14:40
Keynote & Scientific Session 10
Gliomas: Translational Research
GBR 101+102, 1F
Chair(s)
Kyung-Sub Moon (Chonnam National University, Korea)
13:10-13:30
Preliminary report of Navigation guide focus ultrasound combined with avastin for recurrent glioblastoma multiformes patients Pre-recording Only
Kuo Chen Wei (Chung Gung Memorial Hospital, Taiwan)
13:30-13:40
Ultrasound-Assisted Delivery Systems using Microemulsion Platforms Containing a Microbubble and Drugs Onsite
Kihwan Hwang (Seoul National University Bundang Hospital, Korea)
13:40-13:50
Using MRI to Determine Gadolinium Contrast Agent Concentration in Convection-enhanced Delivery Pre-recording Only
Xiaojie Ding (Huashan Hospital, Fudan University, China)
13:50-14:00
Uncovering new therapeutic opportunities for glioblastoma by image-based ex vivo drug-screening Pre-recording + Live Q&A
Sohyon Lee (ETH Zurich, Switzerland)
14:00-14:10
Exploration of biomedical knowledge for recurrent glioblastoma using natural language processing deep learning models Onsite
Bum-Sup Jang (Seoul National University Bundang Hospital, Korea)
14:10-14:20
Dual inhibition of CPT1A and G6PD suppresses glioblastoma tumorspheres Onsite
Soo Jeong Park (Ewha Womans University Seoul Hospital, Korea)
14:20-14:30
Potent bystander effect and tumor tropism in suicide gene therapy using stem cells from human exfoliated deciduous teeth transduced with herpes simplex virus thymidine kinase Pre-recording + Live Q&A
Makoto Horikawa (Hamamatsu University, Japan)
14:30-14:40
A Lignan from Alnus japonica Inhibits Glioblastoma Tumorspheres by Suppression of FOXM1 Onsite
Seung Hoon Lim (Kyung Hee University Hospital, Korea)
13:10-14:40
Keynote & Scientific Session 11
QOL, Epidemiology
GBR 103, 1F
Chair(s)
Zarnie Lwin (University of Queensland, Australia)
John F de Groot (University of California, San Francisco (UCSF), USA)
13:10-13:30
Past Milestones in Neuro-Oncology and Perspective Pre-recording + Live Q&A
Alfred Yung (The University of Texas MD Anderson Cancer Center, USA)
13:30-13:40
Patient-centric design of a neuro-oncology research primer to enhance communication and support of specimen donation for preclinical research Pre-recording Only
Claudia Zizzo (The University of Sheffield, United Kingdom)
13:40-13:50
The Cognitive Function and Health-Related Quality of life in Patients With Glioblastoma throughout the stage of treatment Pre-recording Only
Su Jeong Kim (Severance Hospital, Yonsei University, Korea)
13:50-14:00
Precision Neuro-oncology - A Pilot Analysis of Personalized Treatment in Recurrent Primary Brain Cancer Pre-recording Only
Lazaros Lazaridis (University Medicine Essen, Germany)
14:00-14:10
Risk Assessment Scale of Scalp Adverse Events prior to TTFields Pre-recording Only
Liyun Zhong (Beijing Tiantan Hospital, Capital Medical University, China)
14:10-14:20
Postoperative glioblastoma treatment variation and its outcome in the Dutch elderly population Pre-recording Only
Arthur T.J. van der Boog (University Medical Center Utrecht, The Netherlands)
14:20-14:30
Safety and efficacy of procarbazine and lomustine chemotherapy as a salvage treatment for recurrent adult glioma Onsite
Stephen Ahn (The Catholic University of Korea, Seoul St. Mary's Hospital, Korea)
14:30-14:40
Clinical Characteristics and Outcomes of Primary Brain Tumor Patients Admitted to an Acute Palliative Care Unit of a Tertiary Hospital Onsite
Sung Ji Choi (Seoul National University Bundang Hospital, Korea)
13:10-14:40
Keynote & Scientific Session 12
Pediatric Brain Tumors I
GBR 104+105, 1F
Chair(s)
Seung-Ki Kim (Seoul National University, Korea)
13:10-13:30
Bridging the differences in our management of CNS germ cell tumors Pre-recording + Live Q&A
Mohamed Abdelbaki (Washington University in St. Louis, USA)
13:30-13:40
The treatment outcome and long term prognosis of central nervous system nongerminomatous germ cell tumors – East Asian Multi-institutional Cooperative Study Onsite
Kyung Taek Hong (Seoul National University Hospital, Korea)
13:40-13:50
Prognostic Factors of CNS Germinomas; Histopathological Analyses on 114 Cases from the iGCT Consortium Pre-recording + Live Q&A
Hirokazu Takami (The University of Tokyo Hospital, Japan)
13:50-14:00
Outcomes of intracranial germinoma—a retrospective multinational Asian study on effect of clinical presentation and differential treatment strategies Onsite
Kyung-Nam Koh (Asan Medical Center, University of Ulsan, Korea)
14:00-14:10
Distinct cellular processes are associated with tumor type-related cell subpopulations in pediatric central nervous system tumors Onsite
Min Kyung Lee (Geisel School of Medicine, USA)
14:10-14:20
Inhibiting microcephaly genes as alternative to microtubule targeting agents to treat brain tumors Pre-recording + Live Q&A
Gianmarco Pallavicini (Neuroscience Institute Cavalieri Ottolenghi, Italy)
14:20-14:30
Oncolytic DNX-2401 virotherapy for newly diagnosed pediatric diffuse intrinsic pontine glioma: results of a phase I trial Pre-recording + Live Q&A
Jaime Gallego Perez-Larraya (The University Clinic of Navarra, Spain)
14:40-15:40
Symposium 9
ASNO Meeting for Neuropathology and Neurooncology
Auditorium, 3F
Chair(s)
Koichi Ichimura (Juntendo University, Japan)
Mi Jung Kwon (Hallym University, Korea)
14:40-15:00
Long-term epilepsy-associated neuroepithelial tumors (LEAT) Pre-recording Only
Yueshan Piao (Xuanwu Hospital, Capital Medical University, China)
15:00-15:20
Significance of TERT promoter mutations in malignant brain tumors Pre-recording + Live Q&A
Koichi Ichimura (Juntendo University, Japan)
15:20-15:40
Applied genomics for rare pediatric CNS tumors Pre-recording + Live Q&A
Anthony Liu (Hong Kong University, Hong Kong)
14:40-15:40
Symposium 10
Liquid Biopsy Applications for Brain Tumor
GBR 101+102, 1F
Chair(s)
Kyuha Chong (Samsung Medical Center, Korea)
14:40-15:00
Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid Pre-recording + Live Q&A
Bob S. Carter (Harvard Medical School, USA)
15:00-15:20
Celebrospinal fluid liquid biopsies in medulloblastoma and brain metastasis Pre-recording + Live Q&A
Joan Seoane (Vall d’Hebron Institute of Oncology (VHIO), Vall d'Hebron University Hospital, Spain)
15:20-15:40
Longituidinal profiing of cell-free DNAs in gliomas Pre-recording Only
Houtan Noushmehr (Hermelin Brain Tumor Center & Henry Ford Health System, USA)
14:40-15:40
Symposium 11
Cancer Predisposition Syndrome in Pediatric Brain Tumor
GBR 103, 1F
Chair(s)
Mohamed Abdelbaki (Washington University in St. Louis, USA)
Ji Hoon Phi (Seoul National University, Korea)
14:40-15:10
Medulloblastoma predisposition syndromes: molecular mechanisms and clinical implications Pre-recording Only
Sebastian M. Waszak (University of Oslo, Norway)
15:10-15:40
Genetic counseling, diagnosis and surveillance of pediatric cancer predisposition syndrome Pre-recording + Live Q&A
Yoshiko Nakano (University of Tokyo, Japan)
14:40-15:40
Symposium 12
Evolution in SRS for Brain Metastases
GBR 104+105, 1F
Chair(s)
Seon-Hwan Kim (Chungnam National University, Korea)
14:40-15:00
Recent advance in the concepts and techniques of SRS Pre-recording + Live Q&A
John Suh (Cleveland Clinic, USA)
15:00-15:20
SRS combinated with systemic therapies Pre-recording Only
Cheng Chia Lee (Taipei Veteran General hospital, Taiwan)
15:20-15:40
Neoadjuvant SRS Onsite
Jung-Il Lee (Samsung Medical Center, Sungkyunkwan University, Korea)
16:00-17:00
Symposium 13
Metabolic Targeting for Brain Tumor
Auditorium, 3F
Chair(s)
Vinay Puduvalli (The University of Texas MD Anderson Cancer Center, USA)
Seung Ho Yang (The Catholic University of Korea, Korea)
16:00-16:20
Bioenergetic regulation for glioblastoma Pre-recording Only
Zhimin Lu (Zhejiang University, China)
16:20-16:40
Targeting lipid metabolism for glioblastoma therapy, from de novo synthesis to storage Pre-recording Only
Deliang Guo (Ohio State University, USA)
16:40-17:00
Targeting amino acid synthesis for glioblastoma therapy Pre-recording Only
Daniel A. Tennant (University of Birmingham, United Kingdom)
16:00-17:00
Symposium 14
Modifying Glioblastoma Microenvironment with Local Therapies
GBR 101+102, 1F
Chair(s)
Joo-Young Kim (National Cancer Center, Korea)
16:00-16:30
Immune modulation of radiotherapy for glioblastoma Pre-recording Only
Michael Lim (Stanford University, USA)
16:30-17:00
5-ALA Sonodynamic Therapy for Glioblastoma Pre-recording Only
Nader Sanai (Barrow Neurological Institute, USA)
16:00-17:00
Symposium 15
Symptom Management in Brain Tumor
GBR 103, 1F
Chair(s)
Young-Hoon Kim (Asan Medical Center, University of Ulsan, Korea)
16:00-16:20
Optimal Management of Specific Symptoms in Brain Tumor Patients Pre-recording + Live Q&A
Susan Chang (University of California, San Francisco (UCSF), USA)
16:20-16:40
Integrating Patient Reported Outcomes into Clinical Practice and Research Pre-recording + Live Q&A
Martin Taphoorn (University of Leiden, The Netherlands)
16:40-17:00
Providing Palliative Care in Neuro-Oncology Patients: A Special Population Onsite
Yu Jung Kim (Seoul National University, Korea)
16:00-17:00
Symposium 16
CNS Tumors Outside the Gene Mutation Box
GBR 104+105, 1F
Chair(s)
Jong-Il Kim (Seoul National University, Korea)
16:00-16:20
Oncogenesis of germ cell tumors Pre-recording + Live Q&A
Koichi Ichimura (Juntendo University, Japan)
16:20-16:40
Oncogenesis of central neurocytomas Onsite
Jong-Il Kim (Seoul National University, Korea)
16:40-17:00
Oncogenesis of embryonal tumours with multilayered rosettes Pre-recording Only
Marcel Kool (University of Heidelberg, Germany)
17:00-18:30
Keynote & Scientific Session 13
Gliomas: Genomics, Metabolism
Auditorium, 3F
Chair(s)
G One Ahn (Seoul National University College of Veterinary Medicine, Korea)
17:00-17:20
Epigenetic vulnerabilities in glioma – biomarkers and treatment opportunities Pre-recording + Live Q&A
Monika Hegi (Lausanne University, Switzerland)
17:20-17:30
Identification of glioblastoma origin cells in subventricular zone Onsite
Seok-Gu Kang (Severance Hospital, Yonsei University, Korea)
17:30-17:40
DNA damage drives DNA methylation alterations in glioblastoma Pre-recording Only
Aram Modrek (New York University Grossman School of Medicine, USA)
17:40-17:50
Identification and validation of a novel twenty-three Long non-coding RNAs signature as a prognostic biomarker in glioma Pre-recording Only
Xiaochen Niu (Shanxi Medical University, China)
17:50-18:00
An AMP-activated protein kinase- PGC-1α axis mediates metabolic plasticity in glioblastoma Pre-recording + Live Q&A
Michael W. Ronellenfitsch (University Hospital Frankfurt, Germany)
18:00-18:10
The EGFRvIII transcriptome in glioblastoma, a meta-omics analysis Pre-recording Only
Pim J. French (Erasmus MC Cancer Institute, The Netherlands)
18:10-18:20
Hypoxia upregulates SLC25A39, the putative mitochondrial glutathione transporter, to support glioblastoma growth and metabolism Pre-recording Only
Katherine Eales (University of Birmingham, United Kingdom)
18:20-18:30
A connectivity signature for glioblastoma Pre-recording + Live Q&A
Tobias Kessler (University Hospital Heidelberg, Germany)
17:00-18:30
Keynote & Scientific Session 14
Gliomas: Clinical Trials
GBR 101+102, 1F
Chair(s)
Seung Ho Yang (The Catholic University of Korea, Korea)
17:00-17:20
Gene-and oncolytic-based clinical trials for GBM Pre-recording Only
Ennio Antonio Chiocca (Harvard Medical School, USA)
17:20-17:30
Bevacizumab plus irinotecan with or without gamma knife radiosurgery after failure of concurrent chemo-radiotherapy for high-grade glioma Onsite
Jeong Hwa Kim (Samsung Medical Center, Korea)
17:30-17:40
Phase 2 Study of VAL-083 and Radiotherapy in Newly Diagnosed MGMT-unmethylated GBM Pre-recording + Live Q&A
Chengcheng Guo (Sun Yat-sen University Cancer Center, China)
17:40-17:50
First report from the meta-analysis of the randomized trials NORDIC, NOA-8 and CE.6 on elderly patients with glioblastoma Pre-recording + Live Q&A
Annika Malmstrom (Linköping University, Sweden)
17:50-18:00
PriCoTTF Trial: A phase I/II trial of TTFields prior and concomitant to radiotherapy in newly diagnosed glioblastoma Pre-recording Only
Sied Kebir (University Medicine Essen, Germany)
18:00-18:10
SPARE trial: Scalp sparing radiation with concurrent temozolomide and Tumor Treating Fields (200 kHz) for patients with newly diagnosed glioblastoma Pre-recording Only
Wenyin Shi (Thomas Jefferson University, USA)
18:10-18:20
Overcoming radiation resistance using mycophenolate mofetil in recurrent glioblastoma Pre-recording Only
Yoshie Umemura (University of Michigan, USA)
18:20-18:30
GammaTile brachytherapy in the treatment of recurrent glioblastomas Pre-recording + Live Q&A
Clark Chen (University of Minnesota, USA)
17:00-18:30
Keynote & Scientific Session 15
CNS Lymphoma
GBR 103, 1F
Chair(s)
Heon Yoo (National Cancer Center, Korea)
Frank Anton Giordano (University Medical Center Mannheim, Germany)
17:00-17:20
PCNSL - Current Standard of Care and Novel Therapeutic Development Pre-recording + Live Q&A
Motoo Nagane (Kyorin University, Japan)
17:20-17:30
Hypo-trimethylation of histone H3 lysine 4 and hyper-di/trimethylation of histone H3 lysine 27 as the epigenetic markers of poor prognosis for primary central nervous system lymphoma patients Onsite
Young Zoon Kim (Samsung Changwon Hospital, Korea)
17:30-17:40
MYD88 as a marker in liquid biopsy in Primary Central Nervous System Lymphoma diagnosis. A prospective monoinstitutional series Pre-recording Only
Edoardo Pronello (University and City of Health and Science Hospital, Italy)
17:40-17:50
Effective regimen of high-dose methotrexate plus temozolomide for primary central nervous system lymphoma Pre-recording Only
Jun-ping Zhang (Sanbo Brain Hospital Capital Medical University, China)
17:50-18:00
Clinical experience with rituximab and temozolomide with radiation in treatment of recurrent and refractory primary central nervous system lymphoma in Two Tertiary Philippine Hospitals: a retrospective analysis Pre-recording + Live Q&A
Almira Doreen Abigail Apor (Philippine General Hospital, Philippines)
18:00-18:10
The vanishing tumor phenomenon in the diagnosis of primary CNS lymphoma Onsite
Eunji Yim (University of Michigan, USA)
18:10-18:20
BuTT High-dose chemotherapy supported by autologous stem cell transplant in relapsed or refractory primary CNS lymphoma Pre-recording + Live Q&A
Motoo Nagane (Kyorin University, Japan)
18:20-18:30
Clinical Outcome of RTOG 9310 protocol for Primary Central Nervous System Lymphoma; Single Center Experience of 87 patients Onsite
Young Zoon Kim (Samsung Changwon Hospital, Korea)
17:00-18:30
Keynote & Scientific Session 16
Pediatric Brain Tumors II
GBR 104+105, 1F
Chair(s)
Rakesh Jalali (Apollo Proton Cancer Centre, India)
Joo Ho Lee (Seoul National University, Korea)
17:00-17:20
Pitfalls to be avoided in pediatric brain tumor surgery Pre-recording Only
Young-Soo Park (Nara Medical University, Japan)
17:20-17:30
Deep learning for automatic segmentation and volumetric assessment of pediatric brain tumors: A multi-institutional study Pre-recording Only
Lily Kim (Stanford University, USA)
17:30-17:40
Establishment of centralized integrated diagnostic system for pediatric brain tumors: A report from Japan Children’s Cancer Group (JCCG) Pre-recording + Live Q&A
Yoshiko Nakano (The University of Tokyo Hospital, Japan)
17:40-17:50
Gentle image-guided radiation therapy protocol for pediatric patients Onsite
Nalee Kim (Samsung Medical Center, Korea)
17:50-18:00
Prognostic significance of whole chromosomal aberration signatures in non-metastatic medulloblastomas treated with 18 Gray of craniospinal irradiation Pre-recording + Live Q&A
Kohei Fukuoka (Saitama Children's Medical Center, Japan)
18:00-18:10
Combination of irradiation with lithium in a mouse model of medulloblastoma Pre-recording + Live Q&A
Yana Ruchiy (Karolinska Institute, Sweden)
18:10-18:20
CITK loss leads to DNA damage accumulation impairing homologous recombination by BRCA1 mislocalization in medulloblastoma Pre-recording + Live Q&A
Giorgia Iegiani (Neuroscience Institute Cavalieri Ottolenghi, Italy)
18:20-18:30
Molecular typing and mutation spectrum of Chinese children with medulloblastoma were identified by Next-generation sequencing Pre-recording Only
Juan Li (Gangdong Sanjiu Brain Hospital, China)
18:40-21:00
Gala Dinner
Harmony Ballroom, InterContinental Seoul Coex
07:00-08:00
Opening Symposium 9
BBB modulation for the Treatment of Brain Tumors
Auditorium, 3F
Chair(s)
Michael Lim (Stanford University, USA)
Chae-Yong Kim (Seoul National University, Korea)
07:00-07:20
Blood-Brain Barrier Modulation for the Treatment of Brain Tumors Pre-recording + Live Q&A
Stuart Grossman (Johns Hopkins University, USA)
07:20-07:40
Neuronavigation-guided focused ultrasound (NaviFUS) for recurrent glioblastoma Pre-recording + Live Q&A
Pin-Yuan Chen (Chang Gung Memorial Hospital at Keelung, Taiwan)
07:40-08:00
Focused ultrasound mediated BBB opening using FUS-sensitizing nanoparticle complex: Might it give us the novel paradigm for brain tumor treatment? Onsite
Kihwan Hwang (Seoul National University, Korea)
07:00-08:00
Opening Symposium 10
Tumor Microenvironment and Interactions
GBR 101+102, 1F
Chair(s)
Young Zoon Kim (Samsung Changwon Hospital, Sungkyunkwan University, Korea)
07:00-07:20
Glioblastoma scRNAseq Shows Treatment-induced, Immune-dependent Rise In Mesenchymal Cancer Cells, and Structural Variants in Distal Neural Stem Cells Pre-recording Only
Kevin Petrecca (McGill University, USA )
07:20-07:40
Glioblastoma: microenvironment and niche concept Pre-recording + Live Q&A
Sara G.M. Piccirillo (University of New Mexico, USA)
07:40-08:00
Tumor Microenvironment contributing to Glioma Malignancy Pre-recording + Live Q&A
Jinquan Cai (The Second Affiliated Hospital of Harbin Medical University, China)
07:00-08:00
Opening Symposium 11
Overview and Novel Techniques in Radiotherapy for Meningiomas
GBR 103, 1F
Chair(s)
In Ah Kim (Seoul National University, Korea)
07:00-07:20
Optimization of conventional radiation for intracranial meningiomas Pre-recording + Live Q&A
Barbara-Ann Millar (Princess Margaret Cancer Centre, University of Toronto, Canada)
07:20-07:40
Particle therapy for intracranial meningiomas Pre-recording + Live Q&A
Semi B. Harrabi (Heidelberg University Hospital, Germany)
07:40-08:00
Boron neutron capture therapy for malignant meningiomas Pre-recording + Live Q&A
Shinji Kawabata (Osaka Medical and Pharmaceutical University, Japan)
07:00-08:00
Opening Symposium 12
Genomics and Therapeutic Implication of Pediatric CNS Tumors
GBR 104+105, 1F
Chair(s)
Hye Lim Jung (Sungkyunkwan University, Korea)
07:00-07:20
How can we improve the outcome of ependymoma in molecular era? Onsite
Ji Hoon Phi (Seoul National University, Korea)
07:20-07:40
Recent advances in ETMR Pre-recording Only
Marcel Kool (University of Heidelberg, Germany)
07:40-08:00
Molecular stratified treatment for ATRT Zoom Live Lecture
Susan Chi (Harvard Medical School, USA )
08:15-08:45
Keynote Lecture ASNO
Auditorium, 3F
Chair(s)
Seung Hoon Lee (Eulji University, Korea)
08:15-08:45
Optimising care and survivorship in Adolescent and Young Adult CNS tumour population Pre-recording + Live Q&A
Rakesh Jalali (Apollo Proton Cancer Centre, India)
08:45-09:45
Symposium 17
Cutting Edge Approaches for Brain Tumor Treatment
Auditorium, 3F
Chair(s)
Shin-Hyuk Kang (Korea University, Korea)
08:45-09:05
RUNX-targeted “Gene Switch technology” is a new strategy to treat glioblastoma Pre-recording + Live Q&A
Yoshiki Arakawa (Kyoto University, Japan)
09:05-09:25
Transitioning novel surface biomarkers from glioblastoma to meningioma Pre-recording + Live Q&A
Isaac Yang (University of California, Los Angeles (UCLA), USA)
09:25-09:45
Nanoparticle delivery and fluorophore for glioma treatment Onsite
Dokyoung Kim (Kyung Hee University, Korea)
08:45-09:45
Symposium 18
How to See and Treat in Brain Tumors (PDD & PDT)
GBR 101+102, 1F
Chair(s)
Euihyun Kim (Severance Hospital, Yonsei University, Korea)
08:45-09:05
Near Infrared EGFR Targeted Fluorescence Guided Surgery Pre-recording Only
Gordin Li (Stanford University, USA)
09:05-09:25
Intraoperative photodynamic therapy of glioblastoma Zoom Live Lecture
Walter Stummer (Munster University Hospital, Germany)
09:25-09:45
Clinical practice of PDT and PD for malignant brain tumors using Talaporfin sodium and semiconductor laser Pre-recording Only
Jiro Akimoto (Tokyo Medical University, Japan)
08:45-09:45
Symposium 19
Telomere and Glioma
GBR 103, 1F
Chair(s)
Chul-Kee Park (Seoul National University, Korea)
08:45-09:05
Telomere mantenance mechanisms in gliomas Onsite
Chul-Kee Park (Seoul National University, Korea)
09:05-09:25
Metabolic regulation of TERT and glioma treatment Pre-recording Only
Zhimin Lu (Zhejiang University, China)
09:25-09:45
Features and functions of TERT promoter duplications Pre-recording + Live Q&A
Joseph Costello (University of California, San Francisco (UCSF), USA)
08:45-09:45
Symposium 20
Systemic Treatment of Brain Metastasis and Leptomeningeal Metastasis
GBR 104+105, 1F
Chair(s)
Sung Hwan Kim (The Catholic University of Korea, Korea)
08:45-09:05
Systemic Management of CNS Metastases in Lung Cancer Onsite
Yun-Gyoo Lee (Samsung Medical Center, Sungkyunkwan University, Korea)
09:05-09:25
Systemic Management of CNS Metastases in Breast Cancer Onsite
Hee Jun Kim (Chung-Ang University, Korea)
09:25-09:45
Intrathecal Chemotherapy and Radiation Therapy for Leptomeningeal Metastases Pre-recording Only
Emilie Le Rhun (University of Zurich, Switzerland)
10:00-11:30
Keynote & Scientific Session 17
Low Grade Gliomas
Auditorium, 3F
Chair(s)
Sung Jin Cho (Soonchunhyang University, Korea)
10:00-10:20
Critical Issues in the Management of Lower Grade Gliomas in the Era of Precision Medicine Pre-recording Only
Riccardo Soffietti (University of Turin, Italy)
10:20-10:30
DNA methylome analysis suggested the presence of “true” IDH-wildtype lower-grade gliomas Pre-recording + Live Q&A
Kaishi Satomi (National Cancer Center Hospital, Japan)
10:30-10:40
IDH1-mutant, alternative lengthening of telomeres (ALT) -dependent gliomas use the deubiquitinase BRCC3 to degrade cytosolic cGAS and avoid cGAS-STING-mediated activation of innate immunity. Pre-recording Only
Joydeep Mukherjee (University of California, San Francisco (UCSF), USA)
10:40-10:50
KITENIN leads to TMZ-resistance in MGMT-unmethylated glioblastoma through enhancement of CD44 and ALDH1A1 Onsite
Kyung-Sub Moon (Chonnam National University Hwasun Hospital, Korea)
10:50-11:00
Transcriptome analysis identifies a set of novel genes, which explains the heterogenous behaviour of Anaplastic astrocytoma IDH mutant tumors Pre-recording + Live Q&A
Harsha S. Sugur (National Institute of Mental Health and Neuro Sciences, India)
11:00-11:10
The epigenetic evolution of gliomas associates with malignant transformation after standard treatment Pre-recording Only
Tathiane Malta (University of Sao Paulo, Brazil)
11:10-11:20
Extra-domain B of fibronectin as an alternative target for drug delivery and a cancer diagnostic and prognostic biomarker for malignant glioma Onsite
Kyuha Chong (Samsung Medical Center, Korea)
10:00-11:30
Keynote & Scientific Session 18
Meningiomas, Schwannomas I
GBR 101+102, 1F
Chair(s)
Shin Jung (Chonnam National University, Korea)
10:00-10:20
Jugular foramen tumors: anatomy and surgical resection Pre-recording Only
Ying Mao (Hua Shan Hospital, Fudan University, China)
10:20-10:30
Adjuvant radiotherapy versus observation following gross total resection for atypical meningioma: a systematic review and meta-analysis Onsite
Min-Sung Kim (Seoul National University Hospital, Korea)
10:30-10:40
Risk stratification to define the role of radiotherapy in benign and atypical meningioma: A recursive partitioning analysis Onsite
Joo Ho Lee (Seoul National University Hospital, Korea)
10:40-10:50
Radiotherapy in the management for Intracranial Meningioma: A Systematic Review and Network Meta-analysis Pre-recording Only
Jo-Celine Leong (St. Luke's Medical Center, Philippines)
10:50-11:00
Adjuvant Radiotherapy Versus Surveillance for Grade 2 Intracranial Meningiomas: A Multicenter Study Onsite
Chan Woo Wee (Seoul National University BORAMAE Medical Center, Korea)
11:00-11:10
Contralateral subfrontal approach for the tumberculum sellae meningioma: patient-selection, techniques and outcomes Onsite
Yeong Jin Kim (Chonnam National University Hwasun Hospital, Korea)
11:10-11:20
The Behavior of Residual Tumors following Incomplete Surgical Resection for Vestibular Schwannomas Onsite
Hun Ho Park (Gangnam Severance Hospital, Yonsei University, Korea)
11:20-11:30
Risk factors for progression in vestibular schwannomas after incomplete resection Pre-recording Only
Xuhui Hui (West China Hospital of Sichuan University, China)
10:00-11:30
Keynote & Scientific Session 19
Gliomas: Biomarker, Neuro-imaging
GBR 103, 1F
Chair(s)
Kyu Sung Choi (Seoul National University, Korea)
Manfred Westphal (University Clinic Hamburg-Eppendorf, Germany)
10:00-10:20
Circulating Biomarkers and their Potential Zoom Live Lecture
Manfred Westphal (University Clinic Hamburg-Eppendorf, Germany)
10:20-10:30
DCE-MRI biomarkers of glioma cytoablation efficacy and subsequent recurrence in a preclinical model Pre-recording + Live Q&A
Tavarekere Nagaraja (Henry Ford Health System, USA)
10:30-10:40
Use of Neuroimaging Techniques in Glioma Patients – Results of an International Survey on behalf of the EORTC Brain Tumor Group Pre-recording Only
Philipp Lohmann (Research Center Juelich (FZJ), Germany)
10:40-10:50
Analysis of anatomical invasion pattern of gliomas: Special consideration of the parietooccipital fissure and medial posterior temporal gliomas Pre-recording + Live Q&A
Ichiyo Shibahara (Kitasato University, Japan)
10:50-11:00
Computational anatomic analysis to evaluate the impact of tumor treating fields (TTFields) on brain anatomy Pre-recording Only
Andreas Hottinger (Lausanne University Hospital, Switzerland)
11:00-11:10
Gliomas’ functional connectivity and its relevance to patients' survival Pre-recording Only
Giulia Sprugnoli (University of Parma (Italy), Harvard Medical School (US), Italy)
11:10-11:20
Value of Thallium-201 SPECT/SPECT-CT Brain imaging in Differentiating Malignant from Nonmalignant Lesions: A Comparative Case-Series Study with Pathologic and/or Clinical Correlation Pre-recording + Live Q&A
Nicole Girlyn Pang (St Luke's Medical Center, Philippines)
10:00-11:30
Keynote & Scientific Session 20
Metastatic Brain Tumors I
GBR 104+105, 1F
Chair(s)
Ho-Shin Gwak (National Cancer Center, Korea)
10:00-10:20
Systemic therapy for leptomeningeal disease from solid tumors Pre-recording Only
Catherine Han (The University of Auckland, New Zealand)
10:20-10:30
Comparative profiling of extracellular microRNAs in cerebrospinal fluid discriminates leptomeningeal metastasis from different central nervous system tumor status Onsite
Ho-Shin Gwak (National Cancer Center, Korea)
10:30-10:40
Symptomatic Improvement of Metastatic Brain Tumor Patients based on Clinical and Distress Thermometer in Psychotherapy Adjunction Pre-recording Only
Tiara Aninditha (University of Indonesia, Cipto Mangunkusumo Hospital, Indonesia)
10:40-10:50
Cancer cells outcompete macrophages for extracellular iron in leptomeningeal metastasis Pre-recording Only
Adrienne Boire (Memorial Sloan Kettering Cancer Center, USA)
10:50-11:00
Gene Alternation of Cerebrospinal Fluid in Patients with Leptomeningeal Metastases of Lung Adenocarcinoma using Next-Generation Sequencing Pre-recording Only
Linbo Cai (Guangdong Sanjiu Brain Hospital, China)
11:00-11:10
Interobserver variability of the imaging assessment of leptomeningeal metastasis: a joint EORTC BTG and RANO effort Pre-recording Only
Emilie Le Rhun (University Hospital Zurich, Switzerland)
11:10-11:20
Anti-EGFR VHH-armed death receptor ligand-engineered stem cells have therapeutic efficacy in basal-like breast cancer brain metastasis Pre-recording + Live Q&A
Yohei Kitamura (Tokyo Saiseikai Central Hospital, Japan)
11:20-11:30
Evolution of the Tumor Microenvironment toward Immune-Suppressive Seclusion during Brain Metastasis of Breast Cancer: Implications for Targeted Therapy Onsite
Myung-Giun Noh (Chonnam National University Hwasun Hospital, Korea)
11:30-13:00
Keynote & Scientific Session 21
Multi-disciplinary Approach
Auditorium, 3F
Chair(s)
Ki Seong Eom (Wonkwang University, Korea)
James Balogun (University of Ibadan, Nigeria)
11:30-11:50
The highs and lows of surgical neurooncology in an LMIC- the patient, practice and organized neurooncology Pre-recording Only
James Balogun (University of Ibadan, Nigeria)
11:50-12:00
The Nutritional Status of Patients with Primary and Secondary Brain Tumor and The Affecting Factors in Indonesia National Referral Hospital Pre-recording Only
Gloria Tanjung (University of Indonesia, Cipto Mangunkusumo Hospital, Indonesia)
12:00-12:10
Changes in Neurocognitive Function After Proton versus Photon Radiotherapy for Central Nervous System Tumors Onsite
Kristine N. Kim (University of Pennsylvania, USA)
12:10-12:20
Unmet Supportive Care Needs and Their Influencing Factors in Primary Brain Tumor Patients Receiving Postoperative Radiation Therapy Onsite
Ye Ri Noh (Severance Hospital, Yonsei University, Korea)
12:20-12:30
Discovery and validation of a pre-diagnostic latent metabolic biomarker for glioma Pre-recording + Live Q&A
Sebastian Jonsson (Umea University, Sweden)
12:30-12:40
Epilepsy may convey inferior survival in patients with malignant brain tumors Pre-recording + Live Q&A
Hans-Georg Wirsching (University of Zurich, Switzerland)
12:40-12:50
Positional effect of preoperative neuronavigational magnetic resonance image on accuracy of posterior fossa lesion localization Onsite
Yun-Sik Dho (Chungbuk National University Hospital, Korea)
12:50-13:00
Effect of Orbitotomy on Surgical Freedom in Endoscopic Transorbital Approach (ETOA) to the skull base : An Anatomical Study Pre-recording + Live Q&A
Chat Fong Ng (Queen Elizabeth Hospital, Hong Kong)
11:30-13:00
Scientific Session 22
Meningiomas, Schwannomas II
GBR 101+102, 1F
Chair(s)
Je Beom Hong (Sungkyunkwan University, Korea)
Kevin Chua (National Cancer Centre Singapore, Singapore)
11:30-11:40
Proteomic analysis of genetically stratified meningioma Pre-recording Only
Clemens Oliver Hanemann (University of Plymouth, United Kingdom)
11:40-11:50
A perivascular stem cell underlies vertebrate meningeal tumorigenesis Pre-recording Only
Abrar Choudhury (University of California, San Francisco (UCSF), USA)
11:50-12:00
Molecular profile of radiation-induced meningiomas Pre-recording Only
Wenya Linda Bi (Brigham and Women's Hospital, Harvard Medical School, USA)
12:00-12:10
Diagnostic and Prognostic Methylation-based Classifiers using Liquid Biopsy Specimens from Patients with Meningiomas Pre-recording Only
Grayson Herrgott (Henry Ford Health System, USA)
12:10-12:20
Automated meningioma segmentation and volumetry using a nnU-Net-based architecture on contrast-enhanced MRI Onsite
Ho Kang (Seoul National University Hospital, Korea)
12:20-12:30
Clinical Characteristics and Results of Radiosurgery for Post-Operative High Grade Meningiomas Pre-recording Only
Phan Duong (Vietnam National Cancer Hospital, Vietnam)
12:30-12:40
Deep learning-based predictive model of peri-tumoral edema following Gamma Knife radiosurgery for meningioma Onsite
Kyung Hwan Kim (Chungnam National University Hospital, Korea)
12:40-12:50
Adjuvant radiotherapy for atypical meningiomas is associated with improved progression free survival Pre-recording + Live Q&A
Isaac Yang (University of California, Los Angeles (UCLA), USA)
12:50-13:00
Outcomes after stereotactic radiosurgery for Meckel's cave meningiomas with trigeminal neuralgia Onsite
So Young Ji (Seoul National University Bundang Hospital, Korea)
11:30-13:00
Scientific Session 23
Sellar Region Tumors
GBR 103, 1F
Chair(s)
Chae Heuck Lee (Inje University, Korea)
Syed Ather Enam (Aga Khan University Hospital, Pakistan)
11:30-11:40
DNA Methylation Markers Detected in Liquid Biopsy Specimens Differentitate Pituitary Neuroendocrine Tumors from Other Sellar and CNS Diseases Pre-recording Only
Ana Valeria Castro (Henry Ford Health System, USA)
11:40-11:50
Genetic Landscape and Ligand-dependent Activation of Sonic Hedgehog-Gli1 Signaling in Chordomas: A Novel Therapeutic Target Pre-recording Only
Chenlong Yang (Peking University Health Science Center, Peking University Third Hospital, China)
11:50-12:00
Histological subtypes of the growth hormone secreting pituitary adenoma is crucial for both initial and adjuvant therapy Pre-recording Only
Jiun-Lin Yan (Keelung Chang Gung Memorial Hospital, Taiwan)
12:00-12:10
TRIM65 determines the fate of a novel subtype of pituitary neuroendocrine tumors via ubiquitination and degradation of TPIT Pre-recording + Live Q&A
Zhebao Wu (Ruijin Hospital, Shanghai Jiao Tong University, China)
12:10-12:20
Lactate-induced M2 polarization of tumor-associated macrophages promotes the invasion of pituitary adenoma by secreting CCL17 Pre-recording Only
Shaojian Lin (Ruijin Hospital, Shanghai Jiao Tong University, China)
12:20-12:30
Giant Pituitary Adenoma (GPA) score: A novel scoring system to predict postoperative outcomes Pre-recording + Live Q&A
Syed Ather Enam (Aga Khan University Hospital, Pakistan)
12:30-12:40
Endoscopic endonasal versus transcranial resection of adult craniopharyngioma: a meta-analysis Pre-recording + Live Q&A
Mohammad Hamza Bajwa (Aga Khan University Hospital, Pakistan)
12:40-12:50
Application of fusion-fluorescence imaging using indocyanine green in endoscopic endonasal surgery Pre-recording + Live Q&A
Min Ho Lee (The Catholic University of Korea, Uijeongbu St. Mary's Hospital, Korea)
12:50-13:00
Patterns of care in of Craniopharyngioma: Outcomes following multimodality approach of surgery and radiation therapy Pre-recording Only
Jayant Goda (Tata Memorial Hospital, India)
11:30-13:00
Scientific Session 24
Metastatic Brain Tumors II
GBR 104+105, 1F
Chair(s)
Tae Hoon Roh (Ajou University, Korea)
Sith Sathornsumetee (Mahidol University, Thailand)
11:30-11:40
Antiproliferative effects of olanzapine against MCF-7 human breast cancer cells and its molecular interactions with survivin Pre-recording Only
Poojith Nuthalapati (PJ Biousys, USA)
11:40-11:50
Checkpoint-inhibition therapy for brain metastasis from lung cancer is improved by depletion of intratumoral tumor-associated macrophages and microglia (TAM/M) Pre-recording + Live Q&A
Philipp Karschnia (Ludwig Maximilians University, Germany)
11:50-12:00
The sequence of intracranial radiotherapy and systemic treatment with tyrosine kinase inhibitors for gene-driven non-small cell lung cancer brain metastases in the targeted treatment era Pre-recording + Live Q&A
Siran Yang (Chinese Academy of Medical Sciences Cancer Hospital, China)
12:00-12:10
Neurosurgery for central nervous system metastases: the evolving role in the era of personalized cancer therapy Pre-recording + Live Q&A
Joerg-Christian Tonn (Ludwig Maximilians University, Germany)
12:10-12:20
Efficacy of a biweekly 3-Stage stereotactic radiosurgery for large brain metastases: The effect of EGFR tyrosine-kinase inhibitor on tumor response and clinical outcomes Onsite
Ji-Eyon Kwon (Seoul National University Bundang Hospital, Korea)
12:20-12:30
Whole-Brain Radiotherapy vs. Localized Radiotherapy after Resection of Brain Metastases in the Era of Targeted Therapy: A Retrospective Study Onsite
Tae Hoon Roh (Ajou University, Korea)
12:30-12:40
Is there a reason to avoid the neurogenic niches during radiotherapy of patients with brain metastases? Pre-recording Only
Fia Cialdella (University Medical Center Utrecht, The Netherlands)
12:40-12:50
Hippocampal avoidance in WBRT for metastases: Comparative neurocognitive and dosimetric assessment Pre-recording Only (Q&A attendance not confirmed yet)
Vibhay Pareek (National Cancer Institute, All India Institute Of Medical Science, India)
13:10-13:40
Closing Ceremony
Auditorium, 3F
13:10-13:15
Plaque Ceremony
Michael Weller
13:15-13:20
Farewell Address
Yong-Kil Hong
13:20-13:25
Inauguration of the New WFNOS President
Tracy Batchelor
13:25-13:30
Plaque Ceremony
Yong-Kil Hong